What is a CBD?
Cannabidiol or CBD is a non-intoxicating component of the cannabis plant that has tremendous therapeutic potential. Although CBD does not cause as psychoactive effects as THC, it is of considerable interest among scientists, health professionals, and patients using medical cannabis who use CBD-rich products to treat problems such as chronic pain, cancer, Crohn’s disease. , diabetes, rheumatoid arthritis, post-traumatic stress disorder, cardiovascular disease, anxiety, antibiotic-resistant infections, multiple sclerosis, schizophrenia and more.
Scientific research is being conducted in many countries around the world to study the effects of CBD on these and other diseases. Scientists refer to CBD as a “trapping” compound because it exerts a therapeutic effect in a variety of ways, deeply exploring how we function at the physiological and biological levels. Extensive preclinical research and some clinical trials have shown the strong antioxidant, anti-inflammatory, anticonvulsant, antidepressant, antipsychotic, antitumor, and neuroprotective properties of CBD. Cannabidiol is able to alter gene expression and remove beta-amyloid plaque from the brain, a hallmark of Alzheimer’s disease.
Facts about CBD:
CBD stands for cannabidiol, which is one of the active ingredients in the cannabis plant. It is a well-known naturally occurring cannabinoid molecule, or phytocannabinoid, found in the highest amounts in cannabis, i.e. hemp, but in smaller amounts in other plants such as flax or azalea. Like THC, CBD is produced in the inflorescence of the plant, with only negligible amounts in the leaves, stems, and seeds.
Science currently accounts for the existence of more than 100 cannabinoids, with CBD being the second best known and researched alongside THC. CBD, unlike THC, has no psychoactive effect, so it does not cause intoxication, so-called “tearing.” This property is beneficial for patients who want to avoid or reduce the mind-altering effects of cannabis, such as children, pregnant mothers, or the elderly. This cannabinoid has caused a lot of excitement in recent years – and for good reason.
WHO Comment on Therapeutic Effects:
The WHO has published a “review of diseases for which CBD may have therapeutic benefits”. This is derived from research published by Pisanti et al. (2017) in the scientific journal Pharmacology & Therapeutics.
The list of diseases includes:
– Alzheimer’s disease.
– Parkinson’s disease.
– Multiple sclerosis.
– Huntington’s disease.
– Ischemic-hypoxic injury.
– Inflammatory diseases.
– Rheumatoid arthritis.
– Inflammatory bowel and Crohn’s disease.
– Cardiovascular diseases.
– Diabetic complications.
– Nicotine addiction.
One of the most interesting effects of CBD is its ability to interact with other cannabis compounds, such as terpenes. The compounds work together to provide a more beneficial effect to the user than alone. In the words of Dr. Russo, CBD has a “synergistic contribution” to the effects of cannabis on the body.
Why is CBD not psychoactive?
The reason CBD is not psychoactive is that it does not act in the same pathways as THC and binds to CB1 receptors only to a very small extent. CB1 receptors are found in high concentrations in the brain and these pathways are responsible for the psychoactive effects of THC. A study published in 2011 by Current Drug Safety concluded that CBD “does not interfere with psychomotor and psychological functions.” The authors add that several studies suggest that CBD is “well tolerated and safe” even at high doses.
– 350 ml.